Monoclonal antibodies generally termed as mAb or moAb, are made up of identical immune cells and are all clones of an exclusive parent or mother cell. These antibodies can develop a monovalent affinity, by the virtue of which they adhere to the same epitope, which is a part of an antigen that the antibody recognizes.
What Is the Use of Monoclonal Antibodies?
Monoclonal antibodies are used for treating different types of cancers. In fact, they are chiefly used for conducting immunotherapy. Extensive research is being conducted on various types of monoclonal antibodies and other different related proteins.
What Are the Diseases That Can Be Cured by Monoclonal Antibodies?
Some of the most common diseases that can be cured by monoclonal antibodies include:
- Different varieties of cancer
- Rheumatoid Arthritis
- Tumors of various types
- Multiple Sclerosis
Phage Display and Monoclonal Antibody Screening
Monoclonal antibody screening is another very pertinent topic that comes in the foreground while discussing monoclonal antibody. It is the process used to identify the productive cell lines.
Early and timely identification of the productive cell lines helps to give the scale-up activities a shot in its arms. The Phage display screening mechanism is mainly used for identification of affinity antibodies or the peptides. The Phage display is used for:
- Screening the protein interaction
- Analyzing the mechanism and function of a protein
- Protein engineering
- Determining the tumor antigens
To know more about monoclonal antibodies, you can refer to the following link: MyBioSource. This will give you a fair idea of what are the uses of Monoclonal antibodies and why they are bought. Sites like this will give you a holistic picture of different types of Monoclonal antibodies that are available in the market and in the different forms they are available in the market. Some of the sites even provide you the composition of these Monoclonal antibodies, besides informing you about the different diseases they can cure.
Functions of Antibodies
The human immune system generates certain types of antibodies, which attach to the foreign substances called antigens, either neutralizing or destroying them. Thus, antibodies can very well be regarded as the natural defensive shield of the human body.
Important Medication Using Monoclonal Antibodies
These antibodies are used in various types of therapy. They come in handy in blocking specific cell receptors and for destroying the malignant tumor cells. Also, the process of treatment varies. There are three types of medications that are used in treatment that involves monoclonal antibodies – Bexxar, Rituxan, and Herceptin. Of these, Bexxar contains a molecule of radioactive iodine. However, this treatment has certain side effects like shakes, chills, and fever.
Medication involving Herceptin is used to destroy breast cancer cells. Treatment that involves Rituxin comes in handy to treat different types of lymphomas, particularly Non-Hodgkin's Lymphoma.
Conclusion
Therapy involving monoclonal antibodies is an extremely effective procedure and is considered safe for the patients. In fact, the technology is extremely effective when it comes to creating antibodies to fight specific antigens that create various critical medical conditions. That is the reason these antibodies are immensely popular in the medical world and have opened newer avenues to treat previously incurable medical complications.
