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Saturday, October 21, 2017

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MolMed reports top line results of NGR-hTNF in the phase III

By Molmed, published on May 6, 2014

MolMed S.p.A. (MLM.MI) today announced the results of the double-blinded, placebo-controlled Phase III trial of NGR-hTNF versus best investigator choice in 400 patients with malignant pleural mesothelioma who had previously failed a first-line chemotherapy.

Despite not meeting its primary endpoint of improving overall survival (OS) in the entire population, the study showed a statistically significant (unstratified p=0.02; stratified p=0.01) 40% improvement of OS in patients with poorer prognosis who had progressed during or shortly after first-line chemotherapy. These patients represent... (more)

Tags: molmed, ngr-htnf, malignant pleural mesothelioma

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